When we try to keep it value-centric, we may miss the primary keyword and this sends generic signal to Google. how do tackle this?

is it good practice to put primary keywords in meta tags (like meta title, meta description, etc), H2s, URL Slug, and First 100 words?

Sometimes it's fine as it fits naturally, but should we keep the same practice where it looks meaningless or should we use LSI and Semantic Keywords or secondary keywords?